Overview

Homology modeling is an important technique that constructs an atomic-resolution model of the target protein based on its amino acid sequence and an experimental three-dimensional structure of a homologous protein. Homology modeling depends on the identification of one or more already known protein structures possibly to resemble the structure of the target sequence and on the production of an alignment that maps amino acid residues in the target sequence to residues in the template sequence.

Our Services

At CD ComputaBio, we have a dedicated department that provides excellent homology modeling services. Homology modeling is the construction of atomic resolution models of proteins or nucleic acids based on recognizable homology or sequence similarity between the protein or nucleic acid and proteins of known structure. Our top-notch services help clients predict the structure and function of protein sequences. Our service includes but not limited to:

• Protein Modeling

Our protein modeling services help predict the 3D structure of proteins, providing valuable information for understanding protein function and behavior. Our services include homology modeling, fold recognition, and ab initio prediction.

• Antibody Modeling

We also specialize in antibody modeling, an important service for understanding how antibodies interact with their specific antigens. This valuable knowledge helps in the development of therapeutic antibodies and vaccines. Our services include accurate 3D modeling of antibodies based on antibody sequence data.

Modeling Process

Applications

Our homology modeling services play a key role in a wide range of applications in pharmaceutical, biotechnology and academic research:

• Drug discovery: Identification of novel drug targets, rational design of small molecule inhibitors, and virtual screening.
• Enzyme Engineering: Design of enzymes with customized functions for industrial and therapeutic applications.
• Biologics development: rational engineering of antibodies and other biologics to improve affinity and specificity.
• Structural Biology: Understanding protein-protein interactions, dynamics, and functional mechanisms.
• Personalized medicine: Designing patient-specific therapeutic proteins for precision medicine applications.

Deliverables:

At the conclusion of the service, the client receives:

• Final refined homology modeling structure in PDB format.
• Detailed reports and protocols for all relevant algorithms.
• Comprehensive results analysis and interpretation by our experts.
• Ongoing after-sales support and guidance to deal with any difficulties or problems.

Why Choose Us?

• Protein Homology Modeling
• Antibody Homology Modeling
• Enzyme Homology Modeling
• Peptide Homology Modeling
• G Protein-coupled Receptor Modeling Service
• Ion Channel Protein Modeling Service
• Membrane Protein Modeling Service
• Homology Modeling Results Analysis

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