Overview

Drug repositioning, also known as drug repurposing, is the process of identifying new therapeutic uses for existing drugs. It provides a cost-effective and time-saving approach to drug development by utilizing existing knowledge and resources. CD ComputaBio is a leading bioinformatics company specializing in drug repositioning services. With our cutting-edge technology and expertise in network pharmacology, we assist pharmaceutical companies in identifying potential drug candidates for new indications.

Figure 1. Process of Drug Repositioning. (Zhang Z, et al.2020)

Our Services

Our portfolio of drug repositioning services is designed to unlock the latent potential of existing compounds and provide novel strategies for identifying new therapies. Our services include:

• Drug Repositioning

Leveraging advanced computational algorithms and data analysis, we uncover opportunities to repurpose known drugs for new indications, expanding their therapeutic applications and value.

• Drug Repurpose

Through our specialized expertise, we provide comprehensive analysis and evaluation of existing drugs to identify promising candidates for repurposing, enabling the exploration of alternative indications and disease targets.

• Drug Reprofile

Our in-depth profiling services assess the safety, pharmacokinetics, and pharmacodynamics of existing drugs, guiding the identification of new uses or optimizing their therapeutic properties for enhanced efficacy.

• Drug Redirecting

We offer innovative strategies to redirect drug candidates toward new targets or pathways, maximizing their potential to address diverse diseases and biological mechanisms.

• Network Pharmacology Service

Our network pharmacology services integrate multi-omics data and advanced network analysis to elucidate the complex interactions between drugs, targets, and pathways, enabling a comprehensive understanding of drug mechanisms and potential repositioning opportunities.

Figure 2. Our Network Pharmacology Service.

Applications

The drug repositioning services offered by CD ComputaBio have broad applications across the pharmaceutical industry. They can aid in:

• Identifying new therapeutic uses for existing drugs, reducing the time and cost required for drug development.
• Repurposing failed drugs for alternative indications, maximizing their potential, and minimizing financial losses.
• Personalizing treatment regimens by identifying subgroups of patients who would benefit from specific drugs.

Algorithms

At CD ComputaBio, we employ a range of computational algorithms and methods to maximize the effectiveness of our drug repositioning services. These include

• Network-based approaches: Apply network pharmacology strategies to predict drug-target interactions and reveal potential repurposing opportunities.
• Machine learning techniques: Utilizing algorithms such as random forests and support vector machines to analyze large-scale omics data and predict drug-disease associations.

Sample Requirements

To provide the highest quality drug repositioning services, we require specific sample information, including:

Deliverables

Why Choose Us?

• Drug Reposition
• Drug Reprofile
• Drug Redirecting

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