Drug Redirecting

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Overview

CD ComputaBio is a leading company contributing to revolutionary breakthroughs in the pharmaceutical field through drug retargeting services. We specialize in providing state-of-the-art solutions to solve complex bioinformatics challenges in drug retargeting. Our superior expertise lies in the ability to strategically analyze complex molecular systems of drugs and reorient them for more effective applications.

Our Services

Drug Remodeling

We remodel drugs to enhance their effect on targeted areas, by altering their physicochemical properties.

Drug Reanalysis

Our proficient team dives into comprehensive analytical investigations to understand previous drug deployments and identify new beneficial use cases.

Drug Repositioning

We reposition drugs based on new significant medical discoveries or after the understanding of formerly unknown drug interactions.

Identification and Optimization of Potential Drug Targets

Using predictive analytics, we can identify and optimize new drug targets to maximize their efficacy.

Drug Interaction Prediction

Leveraging state-of-the-art technology, we predict potential drug interactions to prevent adverse effects.

Applications

Drug Redirecting has broad applications across a spectrum of therapeutic areas, including oncology, neurology, infectious diseases, and rare disorders. Our services can be applied to repurpose drugs for a wide range of indications, from targeting specific molecular pathways to addressing unmet medical needs in various patient populations.

Algorithms

Our proficient team utilizes sophisticated algorithms to redirect drugs. These include:

Figure 1. Algorithms of Drug Redirecting.

Similarity Ensemble Approach (SEA): SEA aligns drugs and proteins based on their ligand topology.
Proteochemometric Modeling (PCM): PCM studies the interactions between compounds and their targeted protein families.
Substructure-Activity Relationship (SubSAR) Model: SubSAR conducts an analysis based on molecule segments and defines the function of the medicine based on it.
Multi-task Learning Approach: It constructs a predictive model by learning multiple tasks jointly.

Sample Requirements

Figure 2. Sample Requirements of Drug Redirecting Service.

When utilizing our drug retargeting services, we encourage our clients to provide comprehensive information related to the drug candidate and target disease indication. This includes but is not limited to

Chemical structure or molecular characterization of the drug compound
Biological targets or disease pathways of interest
Pharmacological and toxicological characterization of the repurposed drug candidate
Any available data on clinical efficacy or safety in the original or related indications

Deliverables

Figure 3. Deliverables of Drug Redirecting Service.

Upon completion of the drug repurposing analysis, clients are provided with a set of deliverables that provide actionable insights and decision support for drug repurposing programs. Deliverables may include

Screening reports highlighting potential repurposed drug candidates and their interactions with target disease pathways
Computational pharmacology models predicting pharmacokinetic and pharmacodynamic profiles of repurposed drugs
Integration of computational assessments with experimental or clinical data to support informed decision-making on drug repurposing strategies
On-demand consulting and tailored advice from our team of experts to guide subsequent development activities

Why Choose Us?

CD ComputaBio excels in offering state-of-the-art drug redirecting services. Our team of professionals is dedicated to drug repurposing utilizing advanced algorithms. Our unmatched expertise has made us an eminent partner for several pharmaceutical entities worldwide. Let us assist your business and help the world take one step closer to successful disease management. Contact us today to learn more about how CD ComputaBio's drug redirecting can make a difference in your scientific endeavor.

For research use only. Not intended for any clinical use.

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